This guide provides a practical framework for the alignment of Nationally Determined Contributions (NDCs) with Long-Term Low Emission Development Strategies (LT-LEDS) to ensure a coherent and effective pathway towards low-emission and climate-resilient development. It outlines key stages and steps of alignment, including creating aligned governance and stakeholder engagement mechanisms, shaping a clear mid-century vision that would inform short-term targets and policies that avoid carbon lock-in, ensuring consistency between near-term actions and long-term objectives, and aligning financial planning and monitoring systems for both policy documents. The alignment process can be flexible, allowing the order of the steps to be tailored to a country’s specific needs, policy processes, and circumstances. The guide is designed to support not only countries that already have LT-LEDS in place but also those that are in the process of developing them or have not yet started. The guide provides a number of good practice examples from different countries on various aspects of NDCs and LT-LEDS alignment.